NOT among the most common tumors to metastasize to bone?

NOT among the most common tumors to metastasize to bone?

• A. Colon
• B. Breast
• C. Lung
• D. Thyroid

Answer: (A)

Bone metastases arise most often from tumors with a strong tendency for hematogenous spread, and among common adult sources, breast, lung, and thyroid cancers are frequent culprits. These cancers commonly seed bone and create lesions that can be osteolytic or mixed, leading to persistent bone pain or pathology even without a bone injury. Colon cancer, however, more commonly spreads first to the liver via the portal venous system and bone involvement is relatively rare, typically signaling advanced disease when it does occur. So colon cancer is not considered among the most common tumors to metastasize to bone.

Bone metastases arise most often from tumors with a strong tendency for hematogenous spread, and among common adult sources, breast, lung, and thyroid cancers are frequent culprits. These cancers commonly seed bone and create lesions that can be osteolytic or mixed, leading to persistent bone pain or pathology even without a bone injury. Colon cancer, however, more commonly spreads first to the liver via the portal venous system and bone involvement is relatively rare, typically signaling advanced disease when it does occur. So colon cancer is not considered among the most common tumors to metastasize to bone.